Zoledronic acid improves femoral head sphericity in a rat model of perthes disease
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چکیده
منابع مشابه
Zoledronic Acid Improves Femoral Head Shape in a Rat Model of Perthes Disease
INTRODUCTION: No effective non-operative treatments are available for Perthes disease. We have previously reported significant improvement in outcome in traumatic osteonecrosis in growing rats by intervention with zoledronic acid (ZA), a potent third generation bisphosphonate. In this study we examine the effect of ZA on a model of spontaneous osteonecrosis in growing rats. We hypothesized that...
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Background: Femoral head osteonecrosis is a progressive disease with disabling outcomes in hip joint if not treated.This study was designed to compare the effects of zoledronic acid plus vitamin E versus zoledronic acid alone insurgical induced femoral head osteonecrosis in rabbits.Methods: 26 Japanese white adult normal male rabbits at 28-32 weeks old were undertaken surgical femoraldislocatio...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research
سال: 2005
ISSN: 0736-0266,1554-527X
DOI: 10.1016/j.orthres.2004.11.015